“VISION 2020, THE RIGHT TO SIGHT” was the global initiative launched in the year 1999. Drug delivery to the inner eye is still a challenge in ocular therapeutics. Topical administration of drugs to treat ocular disease is accomplished primarily by means of solutions, ointments, and suspensions. These are relatively inefficient as drug delivery systems; often only 1% of the available drug is absorbed by the eye. Ocular iontophoresis is a non-invasive technique which provide convenient route of administration of many therapeutics indications. This review highlights on the basic concept of ocular iontophoresis, iontophoretic device, transcorneal and transscleral iontophoresis of different drugs, emphasizing the current density applied and the treatment duration used by the investigators.
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